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Is the Sequenced Bordetella pertussis strain Tohama I representative of the species?

Caro V, Bouchez V, Guiso N

Institut Pasteur, Molecular Prevention and Therapy of Human Diseases Unit, URA-CNRS 3012, National Center of Reference of Whooping Cough and Bordetelloses, Paris, France. vcaro@pasteur.fr

Subtractive hybridization was carried out to identify differences between the sequenced genome of Bordetella pertussis Tohama I and those of two recently collected isolates. We identified genetic regions specific to recent isolates, old isolates, and isolates of B. parapertussis and B. bronchiseptica species. We conclude that Tohama I strain is not representative of the B. pertussis species.

Published 9 June 2008 in J Clin Microbiol, 46(6): 2125-8.
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